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Why do small ions have more effects on the body? Is there a reference book?

Q.17 Why do small ions have more effects on the body? Is there a reference book?
A statement, which suggests small ions have more effects on the human body than large ions, is found in this literature.
Medical domain - theory and practice of air ion (co-authored by Syouichi Kimura and Masahiro Taniguchi)
Large ions are less likely to be absorbed by the human body because their mobilities and coefficients of diffusion are smaller. Thus, more small ions work on the body and produce more effects compared with the same quantity of large ions. You can also refer to "Q06 Why do some negative ions have more effects on the human body than others?".
 
Author: Masaharu Nemoto
(Universal Plan Co., Ltd.)
Highly Accurate Air Ion Counter inti-PRO NT-C101A
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Highly Accurate Air Ion Counter inti-PRO NT-C101A (Highly Accurate Air Ion Counter)

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Why does exposure to negative ions reduce irritability, tenseness, with increased calmness and stimulation?
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